Cytologically Yours: Unknowns: 201312: Case 5

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Clinical History

80 year old female. Right breast mass FNA.

Cytology

  • CytologicallyYoursUnknowns201312-5-01.jpg
  • CytologicallyYoursUnknowns201312-5-02.jpg
  • CytologicallyYoursUnknowns201312-5-03.jpg
  • CytologicallyYoursUnknowns201312-5-04.jpg

Resident Questions


Surgical Pathology

  • CytologicallyYoursUnknowns201312-5-05.jpg
  • CytologicallyYoursUnknowns201312-5-06.jpg

Cytologic Features

  • Disorganized clusters
  • Small, crowded groups
  • Loss of cohesion
  • Nuclear atypia
  • Nuclei > 2 x size of RBC
  • Conspicuous nucleoli
  • Intracytoplasmic lumens
  • Absence of myoepithelial cells within groups
  • Absence of bipolar nuclei in the background
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