IPLab:Lab 7:Osteosarcoma

Images

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  This is a photograph of the patient prior to surgery. Note the marked swelling of the knee.

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  This is a radiograph showing the tumor in the distal femur.

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  This is another view of the tumor in the distal femur.

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  This is a gross photograph of the surgical specimen with tissue dissected away to demonstrate the tumor mass.

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  These are cut sections of the distal femur containing the tumor. The periosteal involvement is evident from this picture (arrows).

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  This is a low-power photomicrograph of decalcified histologic section from this tumor. Note the blue color (cell nuclei stain blue) of much of this section indicating the increased cellularity of the tumor.

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  This is a higher-power photomicrograph of decalcified histologic section from this tumor. There are areas of osteoid (1) and cellular areas (2).

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  This is a high-power photomicrograph of decalcified histologic section showing the cellularity of the tumor.

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  This high-power photomicrograph demonstrates the cellular growth pattern. Note that the cells are fusiform and they grow in sheets.

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  This high-power photomicrograph demonstrates the growth pattern and the cell morphology.

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  This is a high-power photomicrograph of the tumor cell morphology and the periosteum (arrow).

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  This high-power photomicrograph of the tumor demonstrates the fusiform morphology of the cells. Note the marked variability in size and staining intensity of the nuclei.

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  This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology.

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  This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology.

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  This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology and multiple mitotic figures (arrows).