Difference between revisions of "Cytologically Yours: Unknowns: 201401: Case 5"
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| + | ==Clinical History== | ||
| + | 58 year old female with a pancreatic mass. | ||
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==Cytology== | ==Cytology== | ||
<gallery heights="333px" widths="333px"> | <gallery heights="333px" widths="333px"> | ||
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===Resident Questions=== | ===Resident Questions=== | ||
| − | * <spoiler text="Diagnosis?"> | + | * <spoiler text="Diagnosis?">__NOGLOSSARY__ |
* Mucinous Pancreatic Neoplasm | * Mucinous Pancreatic Neoplasm | ||
** Includes two diagnostic entities: | ** Includes two diagnostic entities: | ||
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** Best diagnosis is "neoplastic cells present, pancreatic mucinous neoplasm" | ** Best diagnosis is "neoplastic cells present, pancreatic mucinous neoplasm" | ||
</spoiler> | </spoiler> | ||
| − | * <spoiler text="What are some of the cytologic features that lead you to the diagnosis?"> | + | * <spoiler text="What are some of the cytologic features that lead you to the diagnosis?">__NOGLOSSARY__ |
* Abundant thick mucin that may look colloid like | * Abundant thick mucin that may look colloid like | ||
* Mucin can be so thick and tenacious it may cause difficulty in aspirating and making smears | * Mucin can be so thick and tenacious it may cause difficulty in aspirating and making smears | ||
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* Single cells or groups trapped in mucus | * Single cells or groups trapped in mucus | ||
</spoiler> | </spoiler> | ||
| − | * <spoiler text="Differential diagnosis?"> | + | * <spoiler text="Differential diagnosis?">__NOGLOSSARY__ |
* Contaminant gastrointestinal | * Contaminant gastrointestinal | ||
** Brush border and interspersed goblet cells is seen in duodenal epithelium | ** Brush border and interspersed goblet cells is seen in duodenal epithelium | ||
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* CAN NOT DIFFERENTIATE BETWEEN IPMN AND MCN ON CYTOLOGY ALONE | * CAN NOT DIFFERENTIATE BETWEEN IPMN AND MCN ON CYTOLOGY ALONE | ||
</spoiler> | </spoiler> | ||
| − | *<spoiler text="What ancillary studies would you order?"> | + | *<spoiler text="What ancillary studies would you order?">__NOGLOSSARY__ |
* CEA levels are >200ng/mL in both MCN and IPMN | * CEA levels are >200ng/mL in both MCN and IPMN | ||
* Amylase will be high in IPMN and low in MCN (due to IPMN connection with the pancreatic duct) | * Amylase will be high in IPMN and low in MCN (due to IPMN connection with the pancreatic duct) | ||
* B72.3 has diffuse cytoplasmic staining in MCN and IPMN | * B72.3 has diffuse cytoplasmic staining in MCN and IPMN | ||
</spoiler> | </spoiler> | ||
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| + | {{Cytologically Yours}} | ||
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| + | [[Category:Unknowns]] | ||
Latest revision as of 20:10, 16 January 2014
Clinical History
58 year old female with a pancreatic mass.
Cytology
Resident Questions
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