Cytologically Yours: Unknowns: 201311: Case 4: Difference between revisions

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* <spoiler text="What extracellular material may be associated with this neoplasm?">
* <spoiler text="What extracellular material may be associated with this neoplasm?">
* Amyloid.</spoiler>
* Amyloid.</spoiler>
==Cytologic Features==
*Variable cytology/histology
*Polygonal, spindled, plasmacytoid
*Intranuclear pseudoinclusions
*Usually uniform, but can have some pleomorphism
*There may be red cytoplasmic granules on DiffQuik and the chromatin is often salt and pepper

Latest revision as of 16:27, 10 January 2014

Clinical History

57 year old female with hypoechoic nodule on ultrasound.

Cytology

Resident Questions

  • What syndrome is associated with this entity?
  • What are the immunohistochemical features?
  • What extracellular material may be associated with this neoplasm?
  • Cytologic Features

    • Variable cytology/histology
    • Polygonal, spindled, plasmacytoid
    • Intranuclear pseudoinclusions
    • Usually uniform, but can have some pleomorphism
    • There may be red cytoplasmic granules on DiffQuik and the chromatin is often salt and pepper