Difference between revisions of "Cytologically Yours: Unknowns: 201311: Case 3"
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==Cytology== | ==Cytology== | ||
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===Resident Questions=== | ===Resident Questions=== | ||
* <spoiler text="Diagnosis?"> | * <spoiler text="Diagnosis?"> | ||
| − | * | + | * Papillary carcinoma. </spoiler> |
* <spoiler text="What are the most common molecular associations?"> | * <spoiler text="What are the most common molecular associations?"> | ||
| − | * | + | * Rearrangements of Ret proto-oncogene on Chromosome 10 (RET/PTC). |
| − | * | + | * Point mutations of BRAF and RAS </spoiler> |
| − | </spoiler> | + | * <spoiler text="What other entities of the thyroid may exhibit intranuclear pseudoinclusions?"> |
| + | *Medullary carcinoma. </spoiler> | ||
| + | |||
| + | ==Cytologic Features== | ||
| + | *Powdery chromatin, grooves, pseudoinclusions, nucleolus | ||
| + | *Crowding and overlapping | ||
| + | *Sheets, papillae | ||
| + | *Variable cytoplasm (scant, squamoid, Hurthle-like, vacuolated) | ||
| + | *Psammoma bodies | ||
| + | *Giant cells | ||
| + | *Bubble gum colloid | ||
| + | *Septated cytoplasm | ||
Latest revision as of 19:54, 10 January 2014
Clinical History
32 year old male with a solid thyroid nodule on ultrasound.
Cytology
Resident Questions
Cytologic Features
- Powdery chromatin, grooves, pseudoinclusions, nucleolus
- Crowding and overlapping
- Sheets, papillae
- Variable cytoplasm (scant, squamoid, Hurthle-like, vacuolated)
- Psammoma bodies
- Giant cells
- Bubble gum colloid
- Septated cytoplasm
