Cytologically Yours: Unknowns: 201311: Case 2: Difference between revisions

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==Clinical History==
==Clinical History==
48 year old male with a solid thyroid nodule on ultrasound.
48 year old male with a 3.5 cm thyroid nodule on ultrasound.


==Cytology==
==Cytology==
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</gallery>
</gallery>


===Resident Questions===
===Resident Questions===
* <spoiler text="Diagnosis?">
* <spoiler text="Diagnosis?">
* Follicular neoplasm </spoiler?">
* Follicular neoplasm). </spoiler>
* <spoiler text="What are the most common molecular associations with follicular neoplasms/ follicular carcinoma?">
* <spoiler text="What are the most common molecular associations?">
* Ras mutations in 48%.
* Ras mutation in 49%.  
* PAX8-PPAR gamma rearrangement in 36%.
* PAX8-PPAR gamma rearrangements in 36%.
</spoiler>


</spoiler>
==Cytologic Features==
* Microfollicles and trabeculae
* Cellular crowding
* Cellular aspirate
* Little to absent colloid
* Monotony

Latest revision as of 14:50, 10 January 2014

Clinical History

48 year old male with a 3.5 cm thyroid nodule on ultrasound.

Cytology

Resident Questions

  • What are the most common molecular associations?
  • Cytologic Features

    • Microfollicles and trabeculae
    • Cellular crowding
    • Cellular aspirate
    • Little to absent colloid
    • Monotony