IPLab:Lab 7:Adenocarcinoma - Revision history

Peter Anderson: /* Autopsy Findings */

2020-07-09T01:16:16Z

‎Autopsy Findings

2020-07-09T01:16:08Z

‎Clinical Summary

2016-08-25T14:20:10Z

‎Journal Articles

2014-01-03T16:23:23Z

2013-08-30T01:38:55Z

‎Images

2013-08-23T19:32:10Z

‎Related IPLab Cases

2013-08-23T19:30:48Z

‎Additional Resources

2013-08-23T04:21:02Z

2013-08-21T15:29:45Z

2013-08-21T14:32:50Z

← Older revision		Revision as of 01:16, 9 July 2020
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	The segment of colon contained numerous polyps and an annular tumor which was 6.7 cm in diameter. Endoscopic examination of the ascending colon revealed two more polyps which were removed.		The segment of colon contained numerous polyps and an annular tumor which was 6.7 cm in diameter. Endoscopic examination of the ascending colon revealed two more polyps which were removed.
−
−	~~== Autopsy Findings ==~~
−	~~The segment of colon contained numerous polyps and an annular tumor which was 6.7 cm in diameter. Proctoscopic examination of the ascending colon revealed two more polyps which were removed.~~

	== Images ==		== Images ==

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 == Clinical Summary ==
-Approximately four months prior to admission, this 68-year-old male began having "sharp, shooting pains" in the lower abdomen. A barium enema at that time was reported as normal. Two months later, the barium study was repeated because of persistent diarrhea and showed a filling defect in the transverse colon. The patient refused to undergo an exploratory laparotomy. During the week prior to this admission, the patient had recurrent diarrhea, cramping abdominal pain, and marked rectal bleeding. He was hospitalized and required 2500 ml of blood to return his hematocrit to normal. A colectomy was done from the hepatic flexure to the rectosigmoid.
+Approximately four months prior to admission, this 68-year-old male began having "sharp, shooting pains" in the lower abdomen.  On admission a CT scan showed a mass in the transverse colon. The patient refused to undergo a laparotomy and declined further treatment.  Six months later he returned with severe abdominal pain and a colectomy was performed.
 == Autopsy Findings ==

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 === Journal Articles ===
 * Yuen ST, Wong MP, Chung LP, Chan SY, Cheung N, Ho J, Leung SY.  [http://www.ncbi.nlm.nih.gov/pubmed/9543668 Up-regulation of lysozyme production in colonic adenomas and adenocarcinomas].  ''Histopathology'' 1998 Feb;32(2):126-32.
 === Images ===

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 File:IPLab7ColonCA9.jpg|This is a segment of distal colon from another case. Note the annular tumor that severely compromises the lumen of the colon. There is dilation of the colon proximal to the tumor.
 </gallery>
 == Study Questions ==

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 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/66-colon/112-carcinoma PEIR Digital Library: Colon Carcinoma Images]
+* [{{SERVER}}/library/index.php?/tags/66-colon/112-carcinoma PEIR Digital Library: Colon Carcinoma Images]
 * [http://library.med.utah.edu/WebPath/GIHTML/GIIDX.html#10 WebPath: Colon and Appendix]

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 == Related IPLab Cases ==
+* [[IPLab:Lab 7:Metastatic Adenocarcinoma|Lab 7: Lung & Liver: Metastatic Adenocarcinoma]]
 {{IPLab 7}}
 [[Category: IPLab:Lab 7]]

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 # decreased intake of protective vitamins.
 It is thought that reduced fiber content leads to decreased stool bulk, increased fecal transit time in the bowel, and an altered bacterial flora of the intestine. Potentially toxic oxidative byproducts of carbohydrate degradation by bacteria are therefore present in higher concentrations in the small stools and are held in contact with the colonic mucosa for longer periods of time. More recent epidemiologic data have raised some doubt about the importance of fiber in the diet but most nutritionalists still recommend high fiber diet to help prevent colon cancer. Moreover, high fat intake enhances the synthesis of cholesterol and bile acids by the liver, which in turn may be converted into potential carcinogens by intestinal bacteria. Refined diets also contain less vitamins A, C, and E, which may act as oxygen radical scavengers.</spoiler>
 {{IPLab 7}}
 [[Category: IPLab:Lab 7]]

← Older revision		Revision as of 14:32, 21 August 2013
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		+	== Clinical Summary ==
		+	Approximately four months prior to admission, this 68-year-old male began having "sharp, shooting pains" in the lower abdomen. A barium enema at that time was reported as normal. Two months later, the barium study was repeated because of persistent diarrhea and showed a filling defect in the transverse colon. The patient refused to undergo an exploratory laparotomy. During the week prior to this admission, the patient had recurrent diarrhea, cramping abdominal pain, and marked rectal bleeding. He was hospitalized and required 2500 ml of blood to return his hematocrit to normal. A colectomy was done from the hepatic flexure to the rectosigmoid.
		+
		+	== Autopsy Findings ==
		+	The segment of colon contained numerous polyps and an annular tumor which was 6.7 cm in diameter. Proctoscopic examination of the ascending colon revealed two more polyps which were removed.
		+
	== Images ==		== Images ==
	<gallery heights="250px" widths="250px">		<gallery heights="250px" widths="250px">