IPLab:Lab 12:Radiation Fibrosis - Revision history

Peter Anderson: /* Autopsy Findings */

2020-07-09T21:12:06Z

‎Autopsy Findings

2020-07-09T21:11:59Z

‎Clinical Summary

2014-01-03T16:37:23Z

2013-08-30T01:48:04Z

‎Images

2013-08-26T15:07:10Z

‎Related IPLab Cases

2013-08-26T15:06:59Z

‎Images

2013-08-26T15:01:25Z

‎Journal Articles

2013-08-26T14:59:49Z

‎Reference

2013-08-23T04:26:50Z

2013-08-21T16:27:58Z

← Older revision		Revision as of 21:12, 9 July 2020
Line 3:		Line 3:

	At autopsy there was metastatic carcinoma in the pericardium, chest wall, diaphragm, both lungs, and mediastinal lymph nodes. Areas of pleural thickening with adhesions and interstitial fibrosis were found involving the anterior aspect of both lungs.		At autopsy there was metastatic carcinoma in the pericardium, chest wall, diaphragm, both lungs, and mediastinal lymph nodes. Areas of pleural thickening with adhesions and interstitial fibrosis were found involving the anterior aspect of both lungs.
−
−	~~== Autopsy Findings ==~~
−
−	There was metastatic carcinoma in the pericardium, chest wall, diaphragm, both lungs, and mediastinal lymph nodes. Severe nonobstructive cardiomyopathy, probably secondary to adriamycin, was found. Areas of pleural thickening with adhesions and interstitial fibrosis were found involving the anterior aspect of both lungs.

	== Images ==		== Images ==

@@ Line 1: / Line 1: @@
 == Clinical Summary ==
-This 60-year-old white female had developed retraction of her left nipple six years earlier, at which time breast carcinoma was found. A radical mastectomy was performed. Examination of the surgical specimens showed metastases in regional lymph nodes and local irradiation was thus administered. Two years later, carcinoma of the right breast was found. Following a modified mastectomy, more irradiation was given. A year later the patient developed recurrences for which chemotherapy (cytoxan and adriamycin) was given. After a two year period without problems, the patient developed decreased exercise tolerance, dyspnea on exertion, shortness of breath, paroxysmal nocturnal dyspnea, and orthopnea increasing in severity over 10 days. Chest examination revealed decreased breath sounds with dullness over the left base. Chest x-ray showed a globose cardiac silhouette and left pleural effusion. A pericardiectomy was done because of suspected cardiac tamponade; however, the patient died soon after the operation.
+At autopsy there was metastatic carcinoma in the pericardium, chest wall, diaphragm, both lungs, and mediastinal lymph nodes. Areas of pleural thickening with adhesions and interstitial fibrosis were found involving the anterior aspect of both lungs.
 == Autopsy Findings ==

@@ Line 23: / Line 23: @@
 File:IPLab12RadiationFibrosis13.jpg|This is a high-power photomicrograph of a recanalized blood vessel in the lung. Notice the anthracotic pigment adjacent to the vessel (arrows).
 </gallery>
 == Study Questions ==

@@ Line 45: / Line 45: @@
 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/2170-radiation_fibrosis PEIR Digital Library: Radiation Fibrosis Images]
+* [{{SERVER}}/library/index.php?/tags/2170-radiation_fibrosis PEIR Digital Library: Radiation Fibrosis Images]
 * [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#10 WebPath: Interstitial Lung Diseases]

@@ Line 47: / Line 47: @@
 * [http://peir.path.uab.edu/library/index.php?/tags/2170-radiation_fibrosis PEIR Digital Library: Radiation Fibrosis Images]
 * [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#10 WebPath: Interstitial Lung Diseases]
 {{IPLab 12}}
 [[Category: IPLab:Lab 12]]

@@ Line 42: / Line 42: @@
 === Journal Articles ===
+* White P.  [http://www.ncbi.nlm.nih.gov/pubmed/11525052 Evaluation of pulmonary infiltrates in critically ill patients with cancer and marrow transplant].  ''Crit Care Clin'' 2001 Jul;17(3):647-70.
 === Images ===

@@ Line 38: / Line 38: @@
 == Additional Resources ==
 === Reference ===
+* [http://emedicine.medscape.com/article/301337-overview eMedicine Medical Library: Interstitial (Nonidiopathic) Pulmonary Fibrosis]
 === Journal Articles ===