IPLab:Lab 10:Histoplasmosis - Revision history

Peter Anderson: /* Images */

2020-07-09T21:53:17Z

‎Images

2020-07-09T21:46:16Z

‎Clinical Summary

2020-07-09T21:46:03Z

‎Autopsy Findings

2014-01-03T16:34:00Z

2013-08-30T01:45:00Z

‎Images

2013-08-24T03:21:23Z

‎Images

2013-08-24T03:20:31Z

‎Related IPLab Cases

2013-08-24T03:20:21Z

‎Journal Articles

2013-08-24T03:19:42Z

‎Reference

2013-08-23T04:24:25Z

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 == Images ==
 <gallery heights="250px" widths="250px">
-File:IPLab10Histo1.jpg|This low-power photomicrograph shows a section of adrenal gland with several irregularly-outlined areas of necrosis.
+File:IPLab10Histo1b.jpg|This low-power photomicrograph shows a section of adrenal gland with several irregularly-outlined areas of necrosis.
 File:IPLab10Histo2.jpg|This higher-power photomicrograph of the previous adrenal gland shows more clearly the irregularly-shaped area of necrosis (arrows).
 File:IPLab10Histo3.jpg|This is an even higher-power photomicrograph of an area of necrosis (arrows). There is loss of cellular detail within this area. There are inflammatory cells present; however, it is difficult to differentiate the inflammatory cells from the native lymphocytes of the adrenal gland--which is a lymph node.

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 == Clinical Summary ==
 For four months before death, this two-year-old black female infant ate poorly and lost weight. When hospitalized, she appeared chronically ill with signs of infection. An exploratory laparotomy showed the patient had enormously enlarged abdominal lymph nodes, the biopsy of which disclosed active histoplasmosis. Despite intensive therapy, the patient died three weeks after admission.
 == Images ==

← Older revision		Revision as of 21:46, 9 July 2020
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	For four months before death, this two-year-old black female infant ate poorly and lost weight. When hospitalized, she appeared chronically ill with signs of infection. An exploratory laparotomy showed the patient had enormously enlarged abdominal lymph nodes, the biopsy of which disclosed active histoplasmosis. Despite intensive therapy, the patient died three weeks after admission.		For four months before death, this two-year-old black female infant ate poorly and lost weight. When hospitalized, she appeared chronically ill with signs of infection. An exploratory laparotomy showed the patient had enormously enlarged abdominal lymph nodes, the biopsy of which disclosed active histoplasmosis. Despite intensive therapy, the patient died three weeks after admission.
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−	~~== Autopsy Findings ==~~
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−	~~Autopsy showed widespread enlargement of lymph nodes, ulcers of the intestines, and enlarged adrenal glands exhibiting multifocal granulomas.~~

	== Images ==		== Images ==

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 File:IPLab10Histo7.jpg|This photomicrograph was taken under oil immersion to show the silver-stained Histoplasma organisms. Some of the organisms appear to be budding (arrows).
 </gallery>
 == Study Questions ==

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 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/263-histoplasmosis PEIR Digital Library: Histoplasmosis]
+* [{{SERVER}}/library/index.php?/tags/263-histoplasmosis PEIR Digital Library: Histoplasmosis]
 * [http://library.med.utah.edu/WebPath/INFEHTML/INFECIDX.html WebPath: Infection]

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 === Journal Articles ===
+* de Pauw BE.  [http://www.ncbi.nlm.nih.gov/pubmed/11429012 Advances in the management of invasive fungal infections in organ transplant recipients: step by step].  ''Transpl Infect Dis'' 2000 Jun;2(2):48-50.
 === Images ===

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 == Additional Resources ==
 === Reference ===
+* [http://emedicine.medscape.com/article/299054-overview eMedicine Medical Library: Histoplasmosis]
 === Journal Articles ===

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 Histoplasma yeasts are phagocytosed by the unstimulated macrophages, multiply within the phagolysosome, and lyse the host cells.</spoiler>
 {{IPLab 10}}
 [[Category: IPLab:Lab 10]]